Bovine Heart Complex II, with traces of Complex III.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/ml
Purification
purified
Storage buffer
HEPES buffered saline
Preservative
0.02% sodium azide
Storage Conditions
4° C
Tested Applications
Dilution *
Immunocytochemistry (ICC)
5 ug/ml
Immunofluorescence (IF)
Assay Dependent
Western Blot (WB)
5 ug/ml
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Background/Target Information
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
原厂资料:
注意事项:
For Research Use Only. Not for use in diagnostic procedures.