Cattle , Fruit fly , Human , Nematode ,Mouse , Rat
Host / Isotype
Mouse / IgG1
Class
Monoclonal
Type
Antibody
Clone
8D10E6
Immunogen
Human recombinant OSCP and PDH-E1-alpha
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/ml
Purification
purified
Storage buffer
HEPES buffered saline
Preservative
0.02% sodium azide
Storage Conditions
4° C, do not freeze
Tested Applications
Dilution *
Immunocytochemistry (ICC)
Assay Dependent
Immunofluorescence (IF)
Assay Dependent
Western Blot (WB)
0.5-1.0 ug/ml
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Background/Target Information
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex.
原厂资料:
注意事项:
For Research Use Only. Not for use in diagnostic procedures.