Human , Mouse , Nematode , Rat ,Zebra fish , Cattle , Fruit fly
Host / Isotype
Mouse / IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
17D95
Immunogen
Bovine Heart Complex I
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/ml
Purification
purified
Storage buffer
HEPES buffered saline
Preservative
0.02% sodium azide
Storage Conditions
4° C, do not freeze
Tested Applications
Dilution *
Western Blot (WB)
1.0 ug/ml
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Background/Target Information
A novel gene associated with Retinoid-IFN-induced Mortality (GRIM) GRIM-19 gene was identified. Antisense expression of GRIM-19 confers a strong resistance against IFN/RA-induced death by reducing the intracellular levels of GRIM-19 protein. Overexpression of GRIM-19 enhances cell death in response to IFN/RA. GRIM-19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination. These data indicate that GRIM-19 is a novel cell death-regulatory molecule.
原厂资料：
注意事项：
For Research Use Only. Not for use in diagnostic procedures.
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