IKB ALPHA ANTIBODY 100 UG

产品编号：397700 品牌：invitrogen 原厂货号：397700
产品分类：抗体 > 一抗 > 蛋白特异性一抗
应用分类：蛋白质研究 > 抗体和纯化的蛋白质 > 抗体和二级检测 > 一抗

包装：

运保温度:

-20°C

到货周期：

登录后查看

标准价：

￥客户可见

会员价：

￥客户可见

积分：

客户可见分

登录之后可加入购物车购买，请您

运费与支付说明：

1.含干冰类产品有运费；

2. 必须现金付款或有信用额度的会员才可以直接发货，否则需要等待现金付款信息。

描述：

^Details
^{Tested species reactivity}	^{Mouse , Human}
^{Host / Isotype}	^{Mouse / IgG1, kappa}
^Class	^Monoclonal
^Type	^Antibody
^Clone	^ZI002
^Immunogen	^{Synthetic peptide derived from the C-terminal region of the human I-kappa-B-alpha protein}
^Conjugate	^Unconjugated
^Form	^Liquid
^{Concentration}	^{0.5 mg/ml}
^Purification	^{Protein A}
^{Storage buffer}	^{PBS, pH 7.4}
^Preservative	^{0.1% sodium azide}
^{Storage Conditions}	^-20°C

^{Tested Applications}	^{Dilution ^*}
^{ELISA (ELISA)}	^{Assay Dependent}
^{Flow Cytometry (Flow)}	^{3-5 µg x 10^6 cells}
^{Immunocytochemistry (ICC)}	^2µg/ml
^{Immunofluorescence (IF)}	^2µg/ml
^{Western Blot (WB)}	^{Assay Dependent}

^{^* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.}

^{Background/Target Information}

^{NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).}

注意事项：

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.