Synthetic peptide derived from the C-terminal region of the human and mouse claudin-1 proteins
Conjugate
Alexa Fluor® 488
Form
Liquid
Concentration
0.5 mg/ml
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 4.0mg/ml BSA
Preservative
0.1% sodium azide
Storage Conditions
4° C, store in dark
Tested Applications
Dilution *
ELISA (ELISA)
0.1-1.0 µg/ml
Immunocytochemistry (ICC)
1-5 µg/ml
Immunofluorescence (IF)
1-5 µg/ml
Immunohistochemistry (Frozen) (IHC (F))
5-10 µg/ml
Immunoprecipitation (IP)
10 µg/test
Western Blot (WB)
1-3 µg/ml
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
Reactivity has been confirmed with human Caco-2 and canine MDCK cell lysates, mouse kidney and intestinal lysates, frozen mouse intestine (jejunum) tissue, and rat kidney homogenates.
Background/Target Information
Claudin-1 is a member of the transmembrane protein family claudins located in cell-cell tight junctions and it acts as a co-receptor for HCV entry into hepatic cells. Claudins are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Claudin-1 is expressed in most tissues such as bladder, fallopian tube, liver, pancreas, prostate, and skin.
原厂资料：
注意事项：
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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