Interleukin-23 (IL-23) is a disulfide-linked heterodimer which consists of a unique p19 subunit and the p40 subunit of IL-12. IL-23 is a proinflammatory cytokine, which is produced by macrophages and dendritic cells upon infections with certain pathogens. The IL-23 receptor is expressed on Th17 cells and IL-23 is responsible for Th17 expansion and stabilization.
Mouse monoclonal antibody to human Interleukin-23 (p19), clone MT155 biotinylated.
MT155 detects the p19 subunit of the IL-23 heterodimer (p40+p19).
Suitable as detection antibody in ELISA and ELISpot (in combination with clones MT86/221, code 3450-3).
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