Interleukin-4 (IL-4) is produced by activated T cells, especially differentiated CD4+ TH2-type cells, and stimulated mast cells and basophils. The most important effects of IL-4 are the regulation of helper T cell differentiation to the TH2 type and the regulation of IgE and IgG4 production by B cells.
The ELISpot kits mentioned below are suitable for the detection of IL-4 in cow and sheep.
Basic ELISpot kit for the detection of bovine IL-4. The kit contains capture mAb, biotinylated detection mAb and Streptavidin-ALP.