2610-1104 recognizes Dehydroepiandrosterone sulphate (DHEAS) and exhibits the following cross reactivies with related hormones and derivatives:
DHEA
69%
5-alpha-Androstendione
5.3%
5 Androstendione
3.6%
4 Androstendione
2.3
Androstendione
3.0%
Testosterone
<0.3%
Androstendiol
<0.4%
Dehydroepiandrosterone (DHEA) is a steroid hormone produced from cholesterol and secreted by several organs including the adrenal glands. It is the precursor of male and female sex hormones (androgens and estrogens). DHEAS is the sulphated version of DHEA. This conversion is reversibly catalysed by sulphotransferase primarily in the adrenals, the liver, and small intestines. In the blood, most DHEA is found as DHEAS with levels that are about 300 times higher than free DHEA.
Application
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visitwww.abdserotec.com/protocols.
Application Name
Yes
No
Not Determined
Suggested Dilution
ELISA
Radioimmunoassays
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
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