2090-1614 recognises the beta subunit of human chorionic gonadotrophin (hCG) and shows 0.5% cross-reactivity with the intact hCG molecule. Negligible reactivity has been observed with hLH, hTSH and hFSH.
hCG is a peptide hormone that is composed of one alpha and one beta subunit. hCG shares a common alpha chain with the pituitary hormones FSH, TSH and LH, but has a unique beta chain which is recognised by this antibody. hCG is secreted by placental syncytiotrophoblasts and stimulates the ovaries to produce steroids that are essential to pregnancy.
Application
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visitwww.abdserotec.com/protocols.
Application Name
Yes
No
Not Determined
Suggested Dilution
Radioimmunoassays
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.
Fusion Partners
Spleen cells from immunised BALB/c mice were fused with cells of the P3X63-Ag 8.653 myeloma cell line