ANTI-MO/RT SDF-1A POLY PUR 200UG

产品编号：14-7991-83 品牌：Thermo试剂原厂货号：14-7991-83
产品分类：抗体 > 一抗 > 蛋白特异性一抗
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2-8℃

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描述：

Description: The polyclonal antibody reacts with both mouse and rat CXCL12 β (SDF-1β) and was generated using E. coli-expressed mouse CXCL12 β as an immunogen. CXCL12 β, also known as pre-B-cell growth-stimulating factor (PBSF) and stromal cell-derived factor-beta (SDF-1β), is a 74-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of CXCL12 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis in mice. CXCL12 has been shown to be chemotactic for lymphocytes. In addition, CXCL12 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells. CXCL12 binding to CXCR4 inhibits HIV-1 entry.