Human , Rabbit , Mouse , Rat , Cattle , Chicken , Clawed frog
Published species reactivity
Human
Host / Isotype
Mouse / IgG1
Class
Monoclonal
Type
Antibody
Clone
T46
Immunogen
Bovine Tau.
Conjugate
Unconjugated
Form
Liquid
Purification
purified
Storage buffer
PBS
Preservative
0.1% sodium azide
Storage Conditions
-20°C
Tested Applications
Dilution *
ELISA (ELISA)
Assay Dependent
Immunocytochemistry (ICC)
Assay Dependent
Immunofluorescence (IF)
Assay Dependent
Immunohistochemistry (IHC)
Assay Dependent
Immunomicroscopy (IM)
Assay Dependent
Immunoprecipitation (IP)
Assay Dependent
Western Blot (WB)
Assay Dependent
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
原厂资料：
注意事项：
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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