CD127-APC, human 30 tests

• 产品编号：130-098-097      品牌：MACS美天旎       原厂货号：130-098-097
• 产品分类：抗体 > 一抗 > 染料标记抗体
• 应用分类：

描述：

Clone MB15-18C9 recognizes the CD127 antigen, which is the α-chain of the IL-7 receptor, a type I membrane glycoprotein. Signaling of IL-7 through the IL-7R requires both IL-7Rα and the common cytokine gamma chain (γc).¹ CD127 can be identified on immature B cells through the early pre-B stage, on thymocytes, and on most mature T cells with transient down-regulation upon activation.^2,3 On regulatory T cells CD127 is absent⁴ and its expression is inversely correlated with FoxP3 expression and suppressive function.^5,6CD127 is also used by thymic stromal derived lymphopoietin (TSLP) as part of a complex.¹

原厂资料：

Clone MB15-18C9 recognizes the CD127 antigen, which is the α-chain of the IL-7 receptor, a type I membrane glycoprotein. Signaling of IL-7 through the IL-7R requires both IL-7Rα and the common cytokine gamma chain (γc).¹ CD127 can be identified on immature B cells through the early pre-B stage, on thymocytes, and on most mature T cells with transient down-regulation upon activation.^2,3 On regulatory T cells CD127 is absent⁴ and its expression is inversely correlated with FoxP3 expression and suppressive function.^5,6CD127 is also used by thymic stromal derived lymphopoietin (TSLP) as part of a complex.¹

注意事项：

For research use only