CD1c (BDCA-1)-FITC, human 30 tests

产品编号：130-098-009 品牌：MACS美天旎原厂货号：130-098-009
产品分类：抗体 > 一抗 > 染料标记抗体
应用分类：

包装：

运保温度:

2–8 °C

到货周期：

登录后查看

标准价：

￥客户可见

会员价：

￥客户可见

积分：

客户可见分

登录之后可加入购物车购买，请您

运费与支付说明：

1.含干冰类产品有运费；

2. 必须现金付款或有信用额度的会员才可以直接发货，否则需要等待现金付款信息。

描述：

The clone AD5¬8E7 recognizes human CD1c, also known as BDCA¬1. CD1c is expressed on a major subpopulation of human myeloid dendritic cells (about 0.3% of blood leukocytes). Blood CD1c (BDCA¬1)⁺ myeloid dendritic cells are CD11c^high, CD123^low, CD4⁺, Lin^–, CD45RO⁺, CD2⁺, CD16^–, CD141 (BDCA¬3)^low, CD303 (BDCA¬2)^–, and CD304 (BDCA-4/Neuropilin¬1)^–. They express myeloid markers (CD13, CD33) as well as Fc receptors (CD32, CD64, FcεRI) and are of monocytoid appearance. A minor proportion of CD1c (BDCA¬1)⁺ myeloid dendritic cells expresses CD14 and CD11b. In blood, CD1c (BDCA¬1) is also expressed on a subpopulation of CD19⁺ small resting B lymphocytes. CD1c (BDCA¬1) expression has also been detected on cortical thymocytes, on Langerhans cells, and on CD1a⁺ dendritic cells generated ex vivo from monocytes or hematopoietic precursor cells. CD1c (BDCA¬1)⁺ myeloid dendritic cells have been designated as type¬1 myeloid dendritic cells (MDC1s). The CD1c antigen is a member of the CD1 family of proteins that are structurally related to MHC class I proteins and mediate the presentation of non¬peptide antigens to T cells.

原厂资料：

The clone AD5¬8E7 recognizes human CD1c, also known as BDCA¬1. CD1c is expressed on a major subpopulation of human myeloid dendritic cells (about 0.3% of blood leukocytes). Blood CD1c (BDCA¬1)⁺ myeloid dendritic cells are CD11c^high, CD123^low, CD4⁺, Lin^–, CD45RO⁺, CD2⁺, CD16^–, CD141 (BDCA¬3)^low, CD303 (BDCA¬2)^–, and CD304 (BDCA-4/Neuropilin¬1)^–. They express myeloid markers (CD13, CD33) as well as Fc receptors (CD32, CD64, FcεRI) and are of monocytoid appearance. A minor proportion of CD1c (BDCA¬1)⁺ myeloid dendritic cells expresses CD14 and CD11b. In blood, CD1c (BDCA¬1) is also expressed on a subpopulation of CD19⁺ small resting B lymphocytes. CD1c (BDCA¬1) expression has also been detected on cortical thymocytes, on Langerhans cells, and on CD1a⁺ dendritic cells generated ex vivo from monocytes or hematopoietic precursor cells. CD1c (BDCA¬1)⁺ myeloid dendritic cells have been designated as type¬1 myeloid dendritic cells (MDC1s). The CD1c antigen is a member of the CD1 family of proteins that are structurally related to MHC class I proteins and mediate the presentation of non¬peptide antigens to T cells.

注意事项：

仅用于科研